Antiphospholipid Antibody Syndrome in Pregnancy Presenting with Severe Thrombocytopenia - A Success Story

Sunil V. Kapur, Leena Awasthi Kapur

Abstract: This article presents a case report of a 26 - year - old pregnant woman diagnosed with primary antiphospholipid syndrome, characterized by severe thrombocytopenia, recurrent miscarriages, and bleeding symptoms. Initially managed with steroids and platelet transfusions, her platelet count improved, allowing the introduction of antithrombotic therapy. She subsequently had a successful pregnancy, delivering a healthy baby via elective cesarean section at 38 weeks gestation. The patient remained stable on low - dose steroids and enoxaparin postpartum. This case highlights the complexity of managing APS during pregnancy, emphasizing a multidisciplinary approach involving hematologic, obstetric, and rheumatologic care to achieve favourable maternal and neonatal outcomes.

Keywords: Antiphospholipid syndrome, thrombocytopenia, pregnancy, antithrombotic therapy, multidisciplinary approach