Tramadol-Induced Hypoglycemia and Increased Risk of Type 2 Diabetes: A Case Report and Comprehensive Literature Review

Dr. Akshay Rajeshchandra Singh

Abstract: Tramadol, a widely prescribed opioid analgesic, has been associated with various metabolic disturbances, including alterations in glucose metabolism. This case report describes a significant instance of tramadol-induced hypoglycemia in an Indian patient without pre-existing diabetes mellitus, highlighting the potential risk of subsequent type 2 diabetes development. A thorough review of literature, including studies from the Indian context as well as foreign pharmacovigilance studies supports understanding tramadol's impact on glucose regulation.

Keywords: tramadol, hypoglycemia, type 2 diabetes mellitus, opioid analgesics, metabolic effects, pain management, Indian population