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Case Studies | Medical Science | India | Volume 13 Issue 3, March 2024

Sporadic Cause of Hemolytic Anemia - A Case Report

Vasantha Kumar VRR | Neeharika VC

Abstract: Hemoglobin J (Hb J) is a rare variant of normal hemoglobin (Hb A) that belongs to distinct group of fast moving Haemoglobin (FMH). It is identified by its unique fast movement on Alkaline Gel Electrophoresis, towards anode when compared with the normal Hb A. Hb J can be differentiated and identified solely from its retention time. Though Hb J cases are often clinically silent, most of them are detected during routine screening or in conjunction with other hemoglobinopathies. Sometimes they can present with life threatening anemia requiring medical intervention. Most often Hb J is associated with other disorders like alpha thalassemia or other hemoglobin variants. We present here a case report of isolated HbJ which is diagnosed after thorough evaluation for recurrent anemia. This is probably first case of Hb J to be reported from our region. This case report demonstrates the need of in - depth evaluation of a case of recurrent anemia.

Keywords: Fast Moving Haemoglobin, Hb J, Hemoglobin J, Coombs Negative Hemolytic anemia, Recurrent Anemia, Hemoglobinopathy

Edition: Volume 13 Issue 3, March 2024,

Pages: 912 - 914