A Rare Case of Splenic Marginal Zone Lymphoma

Dr. Parth Dalal, Dr. Krishnakant Patel, Dr. Nilesh Lalwani, Dr. Aquib Patel

Abstract: Splenic marginal zone lymphoma is a rare non - Hodgkin lymphoma. Although it is an indolent lymphoma, about 10% of patients can be converted to diffuse large B cell lymphoma. Clinical presentation varies from asymptomatic splenomegaly to abdominal pain, early satiety, fullness and weight loss. Splenectomy is instrumental in diagnosis and treatment of a rare subtype of non - Hodgkin lymphoma. A 55 years old female presented with left upper abdominal pain for 1.5 years and generalized weakness for 6 months and on examination grade - 3 splenomegaly was found. Complete blood count suggestive of pancytopenia and USG shows 22cm spleen and bone marrow biopsy was negative for malignant cells. The patient underwent splenectomy and had an uneventful recovery.

Keywords: Splenic Marginal Zone Lymphoma (SMZL), Splenectomy