Dermatofibrosarcoma Protuberans - Cutting through the Complexity

Dr. B. Santhi, Dr. Sunil Ashish

Abstract: Dermatofibrosarcoma protuberans (DFSP) is an uncommon low-grade malignant soft tissue sarcoma, representing less than 0.1% of all malignant neoplasms and 1% of soft tissue sarcomas. It generally manifests in the third and fourth decades of life, with a greater prevalence in males. DFSP originates from dermal fibroblasts and is distinguished by gradual, infiltrative proliferation, local recurrence, and a minimal propensity for metastasis. This case report describes a 17-year-old female with a two-year history of a rapidly growing nodular mass on the anterior chest wall. Diagnostic assessments, comprising MRI, FNAC, and histology, validated the diagnosis. The patient had a broad local excision with negative margins, and immunohistochemistry indicated CD34 positivity. The postoperative follow-up indicated no recurrence. Timely identification, interdisciplinary care, and prolonged surveillance are crucial to enhance outcomes and reduce recurrence risk in DFSP cases.

Keywords: Dermatofibrosarcoma protuberans, Histopathology, local recurrence, Rare Neoplasms, Soft tissue sarcoma

How to Cite?: Dr. B. Santhi, Dr. Sunil Ashish, "Dermatofibrosarcoma Protuberans - Cutting through the Complexity", Volume 13 Issue 12, December 2024, International Journal of Science and Research (IJSR), Pages: 137-138, https://www.ijsr.net/getabstract.php?paperid=SR241128212826, DOI: https://dx.doi.org/10.21275/SR241128212826