International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Doctoral Thesis | Biotechnology | India | Volume 13 Issue 1, January 2024


Antibacterial Activities of Different Solvent Extracts of Centella asiatica (L.) Urb. and its Endophytic Fungi

Shalini Jane Mundu [2] | Priyanka Puran | Anita Mehta [4]


Abstract: Evaluation of the antibacterial properties of fungal endophytes associated with Centella asiatica (L.) Urb., the ethnomedicinal plant widely used in traditional medicine practices, is part of the current study. Considering both molecular characterization and morphological characteristics, five endophytic fungi were isolated and identified namely Cladosporium sp. (F1), Penicillium sp. (F2), Aspergillus sp.(F3), Colletotrichum sp.(F4) and Curvularia sp.(F5). Escherichia coli, Staphylococcus aureus, Klebseilla pneumoniae, and Bacillus cereus are the four pathogenic bacterial strains that were examined for the antibacterial activity of plant extract and its endophytic fungus extract. The lowest concentration of the extract which inhibits any visual growth was considered to be Minimum Inhibitory Concentration(MIC).The zone of inhibition that different extracts produced against selected strains was measured. The results showed that among all endophytic fungal extracts studied F4,Colletotrichum sp. exhibited the highest zone of inhibition against E. coli, while the hydroalcoholic and aqueous extracts of the Centella asiatica leaf sample showed the maximum zone of inhibition against E. coli and S. aureus, respectively.


Keywords: Endophytic fungi, Centella asiatica(L.) Urb., Antibacterial activities, Apiaceae, ethnomedicinal


Edition: Volume 13 Issue 1, January 2024,


Pages: 531 - 535


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