Choroidal Metastasis in Carcinoma Breast: A Case Series

Era Sankhyayan, Aashutosh Sharma

Abstract: Choroidal metastases is the most common ocular malignancy with most common primary tumor located in the breast (47%). Early diagnosis and prompt intervention is required for sight preservation and maintenance of quality of life. Treatment options include local as well as systemic therapy and the choice depends upon the general status of the patient, number of lesions, location and laterality. Systemic therapy includes chemotherapy, hormonal therapy and biological agents whereas local therapy includes external beam radiotherapy, brachytherapy and stereotactic radiotherapy. The response to systemic and localized therapy is generally good, with lesion regression in 94% of cases and preservation of vision in 75% of cases.

Keywords: choroidal metastasis, ocular malignancies, chemotherapy, hormone therapy, stereotactic radiotherapy