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Review Papers | Pathology | India | Volume 12 Issue 8, August 2023
Correlation between the Cytological and Histopathological Analysis of Breast Lesion
Vikas Kumar [11] | Pooja Jaiswal [2] | Pradeep Tandon | Somil Jaiswal | Nausheen Khan
Abstract: Introduction: Breast lesions can be benign or life - threatening. Accurate and timely diagnosis of these lesions is crucial for clinical management and patient outcomes. Cytological and histopathological analysis helps detect breast cancer early and reduce unnecessary surgery. Henceforth, we aimed to find the correlation between the cytological and histopathological analysis of breast lesions. Methodology: In this cross - sectional descriptive study, 85 women with palpable breast lumps were included. Demographic characteristics were documented, and both FNAC and histopathological tests were performed. All data were meticulously recorded and subjected to rigorous statistical analysis. Results: Among the 85 patients, the majority (52.94%) were aged 15 - 30 years. Cytological examination diagnosed 55 patients as benign, with histopathological examination confirming 58 cases as benign. Fibroadenomas were the most prevalent diagnosis in both tests. In the 15 - 30 age group, benign conditions were most common (74.55%), while the 31 - 45 age group showed a relatively higher malignancy rate (33.33%). Out of 58 cases diagnosed as benign on histopathology, 3 were found to be malignant on cytology, while 55 were truly benign. All 24 cases diagnosed as malignant on histopathology were also confirmed as malignant cytologically. FNAC showed a sensitivity of 100.00% and specificity of 88.89%, with a diagnostic accuracy of 96.34%. Conclusion: According to this study, FNAC is a valuable initial diagnostic tool for breast lesions, offering ease, lower discomfort, and cost - effectiveness compared to conventional skin biopsies.
Keywords: Breast lesions, Fine Needle Aspiration Cytology, Histopathology, Grade
Edition: Volume 12 Issue 8, August 2023,
Pages: 258 - 262