Effect of Smoking on CRP and Pulmonary Function Test in Adult Population of Bundelkhand Region

Dr. B. D. Singh | Dr. Vishal Pathak | Dr. Madhurmay

Abstract: Background: Cigarette smoking is the leading preventable cause of mortality that kills an estimated 5 million people annually worldwide. In India smoking is a common habit prevalent in both urban and rural areas. Cigarette smoking has been associated with elevations of CRP levels. Cigarette smoking has extensive effects on various respiratory diseases. This study investigates the impact of smoking and pulmonary function test in adult population of Bundelkhand region. Material and Methods: The Cross sectional study was conducted on 100 patients presenting with clinical features of COPD. The blood levels of CRP were measure and pulmonary functions were done on a computerized spirometer. Results: Most of the smokers were in the age group of 41 - 50 years. Light smokers were commonest, followed by moderate and heavy smokers. Most smokers belonged to rural background and low socio - economic status. CRP levels were found to be elevated in smokers. CRP is significantly related to smoking intensity, duration and pack - years of smoking. All Pulmonary function parameters like FVC, FEV1, FEV1/FVC were found to be significantly reduced in smokers. Conclusion: Elevated CRP levels and significantly reduced pulmonary function parameters in smokers, highlighting the deleterious effects of smoking on pulmonary functions.

Keywords: Smoker, CRP, Spirometry, Pulmonary function test

Edition: Volume 12 Issue 6, June 2023,

Pages: 2243 - 2246