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Case Studies | Pediatrics and Child Health | Slovakia | Volume 12 Issue 6, June 2023
Fatal Pseudomonas Septicemia in a Late Preterm Infant: A Case Report
Abstract: Background: Sepsis is a primary cause of morbidity and mortality among children worldwide. The most frequently isolated etiologic agents in newborn septicemia are Group B streptococci and Escherichia coli. Pseudomonas aeruginosa - related neonatal infections frequently have late onset, nosocomial origin, and epidemic patterns. It is a rare cause of neonatal bloodstream infections in a?uent nations, and the majority of research only mentions its occurrence when an outbreak is present. The management of Pseudomonas sepsis remains challenging despite improvements in newborn care, particularly when prompt and e?ective treatment is required. Regardless of the age of onset, P. aeruginosa must be taken into account in all newborn infections so that early, appropriate, and frequently lifesaving antibiotic therapy can be started. Case presentation: We present the rare case of a 10 - day - old newborn boy who was admitted to the hospital with late - onset sepsis and hypercapnic respiratory failure caused by Pseudomonas aeruginosa infection. The patient soon developed severe metabolic acidosis upon admission for which he was intubated and connected to arti?cial ventilation. Cultures revealed positivity of Pseudomonas aeruginosa in blood and viscera including the lungs, liquor, suprarenal glands and spleen. The treatment regimen consisted of ampicillin - sulbactam, sodium chloride, furosemide, mannitol, sodium bicarbonate and heparin. Conclusion: Pseudomonas aeruginosa infection is frequently associated with fatal late - onset sepsis in neonates. However, the clinical course and prognosis might vary greatly depending on the speci?c serotype, immune status of the patient and associating symptoms and comorbidities should always be considered. Early diagnosis and timely referral are paramount for a favorable outcome.
Keywords: sepsis, septic shock, Pseudomonas aeruginosa, respiratory failure
Edition: Volume 12 Issue 6, June 2023,
Pages: 2183 - 2185