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Analysis Study Research Paper | Cardiology Science | India | Volume 12 Issue 6, June 2023
A Study of Cardiac Troponin I in ST Segment Elevation Myocardial Infarction and its Complications
Dr. Nidhish Nisty | Dr. Shivaling Nisty | Dr. Niranjan Nisty | Dr. Suresh Harsoor
Abstract: Background and Objective: A flawless and prompt approach is required to manage patients with STEMI and its course especially its complications. Many studies earlier have suggested cardiac troponins like troponin I levels are elevated in STEMI and are directly proportional to prognosis of course of the disease. Present study was performed to study the prognostic and diagnostic significance of cardiac troponin I in ST elevation MI and its complications. It was also to study the quantitative correlation of cardiac troponin I with ST elevation MI and its complications. Methodology: Fifty cases were studied from November 2018 to May 2020. Cases diagnosed to have of ST elevation MI as per AHA/ESC/ACC guidelines within 6 hours onset of symptoms. All the patients were examined and investigated according the proforma. They received treatment as per AHA/ESC/ACC guidelines. During hospital stay, they were observed for predefined complications. Results: Among the fifty cases, mean age ? SD in the study group was 53.76?11.03years and ranged from 22 to 70 years. Male patients 36 (72%) outnumbered the female patients 14 (28%) and Male: Female ratio is 2.51: 1. Most common symptom was chest pain (100%) followed by sweating (34%) and pain radiating to arm (34%). Major risk factors were cigarette smoking (62%), Diabetes Mellitus (42%), hypertension (32%). AWMI was more common with 70% of patients and 30% were IWMI. Tenecteplase 30mg was most used as thrombolytic agent administered to 70%of patients. In these patients 92% of them had elevated Cardiac Troponin-I levels and8% had normal Troponin ?I levels. Among these with elevated Troponin-I levels 44%of the patients experienced complications. Most common complications being arrhythmias 45.46% and next being the heart failure 40.9%. Mortality in the study is6%. Interpretation and Conclusion: Cardiac Troponin-I is a reliable diagnostic as well as prognostic indicator in patients with STEMI. The magnitude of Cardiac Troponin-I levels is directly proportional to myocardial damage and adverse course of STEMI including its complications and mortality.
Keywords: Cardiac Troponin I, Myocardial Infarction
Edition: Volume 12 Issue 6, June 2023,
Pages: 1175 - 1178