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Analysis Study Research Paper | Medical Science | India | Volume 12 Issue 6, June 2023
Proportion of Sarcopenia in Cirrhotic Patients of Age More than 18 Years Admitted with Complications at a Tertiary Care Centre in Thrissur District
Dr. Vishnupriya [3] | Dr. Edwin J George | Dr. Sojan George
Abstract: Introduction: Liver cirrhosis patients often have decreased physical activity and protein - energy malnutrition and sarcopenia1. Sarcopenia is part of the frailty which has a predisposition to poor outcomes in chronic liver disease patients2. But this is least addressed domain in cirrhotic patients. Hence purpose of this study is to identify the proportion of sarcopenia in liver cirrhosis patients and its association with different complications3. Methods: This cross sectional study was done in in Department of Gastroenterology of Amala Institute of Medical Sciences over 1.5 year period. Sarcopenia was assessed based on handgrip strength measured using hand grip dynamometer. Results: A total of 130 patients were studied and proportion of sarcopenia was 60% (78 among 130 patients). Sarcopenia was more among females (75%) than males (55.88%). Sarcopenia among Child A - 45.28% Child B - 59.26%, child C - 95.65%, MELD >11 66.33% and in MELD >15 80%. Among 130 patients enrolled in the study 102 (78.43%) patients had ascites among whom 71 (69.61%) had sarcopenia.15 (11.54%) patients had hepatic encephalopathy, 6 (4.62%) had HRS and all of them had sarcopenia.7 (5.38%) had SBP and 5 (71.43%) had sarcopenia.26 patients (20%) had variceal bleed among whom 13 (50%) had sarcopenia. Conclusion: In this study of 130 patients with chronic liver disease admitted with complications 78 patients (60%) were found to have sarcopenia. All patients with HRS and Hepatic encephalopathy had sarcopenia.71.4% of patients with SBP, 69.6% patients with ascites and 50% of patients with variceal bleed had Sarcopenia Proportion of sarcopenia among CLD patients is high and has association with different CLD related complications, hence addressing this problem must be an integral part of CLD management.
Keywords: Sarcopenia, handgrip strength
Edition: Volume 12 Issue 6, June 2023,
Pages: 557 - 560