International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 16 | Views: 351 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Review Papers | Pharmacology Science | India | Volume 12 Issue 8, August 2023 | Popularity: 5.3 / 10


     

Effect of Curcumin in Psoriasis

Makani. Sai Bhargavi, K. Sridevi


Abstract: Psoriasis it is a chronic autoimmune & inflammatory non communicable disease. it is usually highly expressed as inflamed red erythematous plaques which is supported by silvery scales. The presence of these scaly patches is an outcome of the unusual proliferation of excessive epidermis, incomplete cornification and preservation of nuclei in cells of statum corneum. The mechanism of action by which curcumin shows as anti-inflammatory response of TNF-stimulated human endothelial cells by interfering with NF-kB. Furthermore, the curcumin is also capable of preventing the platelet-derived growth factor. Curcumin is also to suppress the excessive production of TNF-? by activated macrophages the curcumin has been shown to directly bind to the receptor-binding sites of TNF-? by covalent and non-covalent interactions, blocking the subsequent TNF-dependent activation of NF-k.


Keywords: Psoriasis, Curcumin, Pathogenesis, Plague, Guttate, Inverse, Pustular, Erythrodermic, Koebner


Edition: Volume 12 Issue 8, August 2023


Pages: 10 - 15



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!
Makani. Sai Bhargavi, K. Sridevi, "Effect of Curcumin in Psoriasis", International Journal of Science and Research (IJSR), Volume 12 Issue 8, August 2023, pp. 10-15, https://www.ijsr.net/getabstract.php?paperid=SR23524114335



Similar Articles

Downloads: 19 | Weekly Hits: ⮙4 | Monthly Hits: ⮙6

Review Papers, Pharmacology Science, India, Volume 13 Issue 7, July 2024

Pages: 128 - 132

Advancements in Pulmonary Hypertension: Defining New Horizons!

Dr. Siriginedi Naga Spandana Priya, Pulagam Vaishnavi Reddy

Share this Article

Downloads: 145

Research Paper, Pharmacology Science, Egypt, Volume 6 Issue 2, February 2017

Pages: 843 - 847

Prevention of Diabetic Retinopathy by Melatonin in Rats with STZ Induced Diabetes Mellitus

Reham E. Masoud

Share this Article



Top