International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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New Innovation and Idea | Health and Medical Sciences | Volume 12 Issue 5, May 2023 | Pages: 928 - 936 | United States


A Clinical Trial Evaluating the Efficacy of Prolistem? Supplement in Men with Non-Obstructive Azoospermia (Primary Testicular Failure)

Mahmoud Abuelhija

Abstract: Introduction: Non-obstructive azoospermia is a common cause of male infertility and remains one of the most challenging conditions to treat, despite advances in gynecology. Prolistem? is a novel treatment for this condition, which utilizes a unique mechanism called the "Spermatogenesis Restarting Process". Objectives: To evaluate the effectiveness of Prolistem? supplement in the therapy of infertile men with nonobstructive Azoospermia. Methods: Eighty-nine patients with non-obstructive azoospermia were enrolled in the study and received Prolistem? supplement for six months. Hormone parameters, including follicle-stimulating hormone (FSH), luteinizing hormone (LH), and testosterone levels, were measured before and after the procedure. Semen analysis was performed after the treatment, and in case of no sperm found, patients were recommended to undergo sperm retrieval techniques such as testicular sperm extraction (TESE) or micro-TESE. All the data required for the study were collected retrospectively from the patients or the hospital records. Results: After six months of Prolistem? supplementation, a significant improvement was observed in the hormone parameters of the patients. The mean FSH level decreased from 18.2 ? 5.6 to 8.4 ? 2.9 mIU/mL (p

Keywords: Azoospermia, Male Infertility, Prolistem, Testosterone, Primary Testicular Failure

How to Cite?: Mahmoud Abuelhija, "A Clinical Trial Evaluating the Efficacy of Prolistem? Supplement in Men with Non-Obstructive Azoospermia (Primary Testicular Failure)", Volume 12 Issue 5, May 2023, International Journal of Science and Research (IJSR), Pages: 928-936, https://www.ijsr.net/getabstract.php?paperid=SR23511225822, DOI: https://dx.doi.org/10.21275/SR23511225822

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