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Research Paper | Ophthalmology | India | Volume 12 Issue 5, May 2023

Our Experience with Retrobulbar Amphotericin-B in Patients of Rhino-Orbital-Cerebral Mucormycosis (ROCM) at GMERS Gotri

Dr. Kamlesh Gendalbhai Damor | Dr. Ruju K. Upadhyaya | Dr. Hemali A. Patel | Dr. Ashwini Sapre

Abstract: Purpose: To evaluate ocular features in Rhino-Orbital-Cerebral Mucormycosis (ROCM) and to study outcome of retrobulbar injection Amphotericin-b in the patients of ROCM following COVID-19. Methods: 118 confirmed cases of ROCM following COVID-19 were analyzed retrospectively. Results: Out of 118 patients, 74 patients had disease in the nose and paranasal sinuses (PNS), 37 showed orbital involvement as well and 7 patients had severe disease involving the brain also. Out of 118 patients, 17 patients were given Retrobulbar Amphotericin-B injection of which 13 recovered well.5 orbital exenterations were done, out of which one patient survived. Conclusion: Retrobulbar Amphotericin ?B injection serves important role in preventing spread of fungus to the brain and improving mortality.

Keywords: COVID-19, Rhino-Orbital-Cerebral Mucormycosis, Retrobulbar Amphotericin-B, exenteration

Edition: Volume 12 Issue 5, May 2023,

Pages: 727 - 729