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Masters Thesis | Pathology | India | Volume 12 Issue 5, May 2023

Platelet Count and its Indices: Early Marker of Neonatal Sepsis

Shreya Tuli | Nanda J Patil | S. R. Kanetkar

Abstract: Introduction: Neonatal sepsis is one of the major factors contributing to the high perinatal and neonatal mortality and morbidity amongst newborns and is a global health challenge. Prompt treatment can decrease the mortality rate. (1, 2) Aims and objectives: The aim of the study was to evaluate the platelet count and platelet indices in cases of neonatal sepsis. Secondary objective is to correlate platelet count and platelet indices with clinical features and other markers of sepsis like blood culture and C - reactive proteins. Materials and Methods: The prospective study lasted two years from July 2020 to August 2022, at a tertiary care hospital where platelet count and its indices were evaluated along with the clinical features of neonates for early diagnosis of neonatal sepsis. Results: A total of 117 cases of neonatal sepsis with male preponderance in the age group of1 - 2 days were obtained. The preterm neonates delivering by caesarian section were more at risk for septicemia. Thrombocytopenia was observed in 78 cases. Increased platelet parameters like mean platelet volume and platelet distribution width were observed in the study.

Keywords: Thrombocytopenia, Neonatal sepsis, Platelet indices in neonatal sepsis, Organisms in neonatal sepsis, C - reactive protein in neonatal sepsis

Edition: Volume 12 Issue 5, May 2023,

Pages: 963 - 966