International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Review Papers | Plant Physiology and Botany | India | Volume 12 Issue 4, April 2023

Role of HDAC in Mediating Homeostasis in Plants during Stress - A Review

Drishya Mukherjee | Nirjhar Dasgupta

Abstract: Crop yield is directly impacted by plant growth and development as well as their ability to respond to changing climatic circumstances. Histone deacetylation is an epigenetic alteration that regulates a number of genes important for biological processes including stress reactions and development. The implications of histone Deacetylation dynamics on vegetative growth, fawn development, fruit ripening, and biotic and abiotic stress responses have been the primary focuses of this study. Histone acetylation dynamics is one of the best-studied PTM processes. Like the majority of other PTMs, acetylation is reversible, and its dynamic management depends on the activity of histone acetyltransferases (HATs) and histone deacetylases (HDACs). Typically, HATs bind acetyl groups (CH3COO -) to lysine residues in both the globular and N-terminal tails of histones to activate genes. However, by restoring the histones to their basal state, which largely results in gene repression, the removal of these acetyl groups by HDACs serves to offset the actions of HATs. In exceedingly rare instances, HATs and HDACs may, respectively, induce the activation and repression of genes. HATs and HDACs both target the histone lysine residues H3K9, H3K14, H3K36, H4K5, H4K8, H4K12, and H4K16 in order to preserve the dynamics of histone acetylation. Hyper-and hypo-acetylation, which are often associated with the activation and repression of certain genes, are the results of the dynamics of histone acetylation. We have also emphasized the information gaps that need to be researched in order to completely understand the role of histone deacetylation dynamics in plants. Finally, a thorough understanding of the dynamics of histone deacetylation might help increase stress resistance and lessen production losses in a variety of crops caused by environmental changes.

Keywords: HDACs, HATs, Epigenetic Modification, Stress Response, Homeostasis

Edition: Volume 12 Issue 4, April 2023,

Pages: 1831 - 1842

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