International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Paediatrics | India | Volume 12 Issue 4, April 2023


Study of Risk factors of Neonatal Sepsis

Rakesh Thamke [4] | Jayvardhan Lade [3] | Rishabh Shah [2]


Abstract: Introduction: Sepsis is the commonest cause of neonatal mortality. Neonatal sepsis is a serious blood bacterial infection in neonate at the age equal to or less than 28 days of life which is manifested by systemic signs and symptom. Sepsis related mortality is largely preventable with prevention of sepsis itself by identifying risk factors of neonatal sepsis, timely recognition, rational antimicrobial therapy and aggressive supportive care. Present study was undertaken to ascertain and study risk factors of neonatal sepsis in tertiary care center. Objectives: To ascertain and study risk factors of neonatal sepsis in tertiary care center. Material & Methods: This prospective observational study was conducted on 372 neonates in NICU of MGM Medical College and Hospital located at Kalamboli. Neonates being admitted to NICU with signs and symptoms of sepsis or presence of predisposing factors for development of sepsis orneonates with suspected sepsis in the NICU were included in study. Result: 372 neonates were included in this study.93.3% of study population had Neonatal risk factors in which Preterm and low birth weight were significant risk factors for sepsis.47.8% of study population had Maternal Risk Factors. The major risk factors were preterm premature rupture of membranes (PPROM) or premature rupture of membranes (PROM) which was present in about 39% of study population.45.7% of study population had fetal risk factors. The major risk factors were fetal tachycardia and bradycardia, suggestive of fetal insufficiency which comprised of 43% of study population. Conclusion: The current study showed maternal, fetal and neonatal risk factors in newborns for neonatal sepsis. Neonatal risk factors have contributed more than maternal and fetal risk factors.


Keywords: Neonatal sepsis, Risk factors, Antimicrobial sensitivity, Newborn, PROM, LBW, Preterm delivery


Edition: Volume 12 Issue 4, April 2023,


Pages: 276 - 281


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