Clinicopathological and Microbiological Study of Chronic Dacryocystitis
Abstract: Objectives: To study the various modes of presentations of chronic dacryocystitis, to analyse the histopathological picture in the lacrimal sac biopsy in chronic dacryocystitis and to define spectrum of pathogens causing dacryocystitis and their culture sensitivity to different antibiotics. Methodology and Methods: A descriptive study was performed in a tertiary care hospital on 60 patients presenting with chronic dacyocystits. Intraoperatively sample from the mucopurulent material found at the bottom of lacrimal sac and sent for culture and sensitivity. Specimen of the lacrimal sac obtained during dacryocystorhinostomy or dacryocystectomy is sent for histopathological examination. Results: 60 patients underwent the study. Bimodal peak was noted in 31-40 years (23.3%) and 61-70 years (25%), commonly seen in females (60%), Epiphora was the most common presenting complaint (43.3%).83.4% had primary acquired nasolacrimal duct obstruction with chronic dacryocystitis, 8.3% had associated mucocele, 3.3% had associated corneal ulcer while 5% had associated mucocele with fistula. Most common organism isolated was Staphylococcus aureus (46.7%), most of the isolated organisms showed sensitivity to Cephazolin (98%), Gatifloxacin (88%) and were resistant to Ciprofloxacin (36%), Chloramphenicol (44%).75% of the cases showed non specific inflammation of the lacrimal sac while 3.3% had hyperplastic changes, 3.3% had fibrotic changes, 5% had dacryocystitis pseudoglandularis and3.3% showed squamous metaplasia of the sac epithelium. Conclusion: Chronic dacryocystitis exists in various forms of etiology and presentation. Prompt surgical treatment helps in prevention and management of its complications. Microbiological and histopathological study of the sac helps in better understanding and further management of the disease.
Keywords: Chronic dacryocystitis; Pathology of sac; Bacterial pathogens; Antibacterial susceptibility and resistance
How to Cite?: Kusagur Shivayogi R, Ram Deepa, "Clinicopathological and Microbiological Study of Chronic Dacryocystitis", Volume 12 Issue 2, February 2023, International Journal of Science and Research (IJSR), Pages: 1668-1673, https://www.ijsr.net/getabstract.php?paperid=SR23221121258, DOI: https://dx.doi.org/10.21275/SR23221121258