Non-Molar Choriocarcinoma Following Miscarriage: A Rare Clinical Entity

Dr. Sonali Gupta, Dr. Ravinder Kalkat

Abstract: This case report presents the rare occurrence of non-molar choriocarcinoma in a 36-year-old female with no documented history of molar pregnancy. The patient presented with recurrent severe bleeding in the first trimester, which led to surgical evacuation. Histological examination revealed non-molar choriocarcinoma, prompting her referral to a regional centre for trophoblastic disease for further management. A retrospective study involving 21 years found the incidence of non-molar choriocarcinoma 1:66 775 relative to live births [1]. Non-molar choriocarcinoma is a rarely reported entity in the literature, emphasizing the diagnostic challenges and need for timely intervention.

Keywords: Non-molar choriocarcinoma, Miscarriage, Trophoblastic neoplasia, Gestational trophoblastic disease