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Analysis Study Research Paper | Cancer Science | Egypt | Volume 10 Issue 3, March 2021

Evaluation of Intellectual Function in Patients with Early Bronchogenic Carcinoma in Upper Egypt

Ahmad M. Shaddad | Waleed Gamal Elddin

Abstract: Background: It's well established that in the course of bronchogenic carcinoma many inflammatory mediators and hypoxemia can affect Intellectual function and cognition through different pathways. This study aims to spotlight the possible cognitive abnormalities in bronchogenic carcinoma patients. Methods: in a case-control study module, twenty-five bronchogenic carcinoma patients and twenty-five age and sex-matched healthy control were enrolled. Mini-mental state examination (MMSE) was used to assess intellectual function in bronchogenic carcinoma patients and the control group. Results: there was significant impairment of the Mini-Mental State Examination questionnaire (MMSE) between the newly diagnosed bronchogenic carcinoma group and normal control. The mean MMSE was (24.52 ? 3.04) in the bronchogenic carcinoma group and (28.12 ? 1.66) in the control group with an observed significant difference between the two groups with a p-value of < 0.0001 emphasizing the early intellectual dysfunction that occurs through the course of early stages of bronchogenic carcinoma. Conclusion: Cognitive dysfunction is observed in the early stages of bronchogenic carcinoma even before any interventional modalities such as chemotherapy, radiotherapy or surgery.

Keywords: Lung Cancer, Cognitive Function, Mini-Mental State Examination

Edition: Volume 10 Issue 3, March 2021,

Pages: 1927 - 1931