International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Case Studies | Radiotherapy & Oncology | India | Volume 12 Issue 11, November 2023 | Rating: 4.3 / 10


Esthesioneuroblastoma: A Rare Case Report

Era Sankhyayan [9]


Abstract: Esthesioneuroblastoma is a rare, malignant neoplasm of neuroectodermal origin in the roof of nasal fossa with incidence rates of less than 5% of nasal cavity tumors. It shows a variable course from being indolent tumor to highly aggressive neoplasm depending upon various factors e.g, kadish classification, hyam grading of tumor, presence of lymph nodal involvement, metastasis, tumor proliferation index, extent of surgical resection, p53 overexpression and deletion of chromosome 11. The clinical manifestations are non specific and include nasal obstruction, epistaxis, hyposmia, headache and exophthalmos. Surgery is the mainline of treatment followed by adjuvant radiotherapy. Despite treatment recurrence rates are as high as 60 % with mean 5 year survival rates of 33%- 87%. We present a post operative case of 27 year old male patient with left proptosis and esthesioneuroblastoma of KADISH type B.


Keywords: Esthesioneuroblastoma, malignant neoplasm, craniofacial resection, radiotherapy


Edition: Volume 12 Issue 11, November 2023,


Pages: 256 - 257


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