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Case Studies | Medical Science | India | Volume 12 Issue 10, October 2023

Allergic Bronchopulmonary Aspergillosis: A Masquerade to Malignancy

Mittal Shubham

Abstract: Allergic bronchopulmonary aspergillosis (ABPA) is an immunologically mediated lung disease that occurs in response to Aspergillus fumigatus which affects primarily asthmatic and cystic fibrosis patients. Central bronchiectasis is a classical radiological presentation of ABPA, but the presentation as total collapse of the lung, pneumothorax, lung mass, or fibrocavitary disease has been rarely described in all cases of asthma, there should be a thorough evaluation for ABPA if there is any abnormal chest radiology present. ABPA may mimic malignancy and there should be a high index of suspicion for the same should be there especially in cases of atopic individuals. Complete history taking and diagnostic work up is needed in such cases which include CT Chest and Fibreoptic Bronchoscopy (FOB). We report a case of ABPA in a 39 year old female with background history of asthma, initially suspected to have bronchogenic carcinoma of the right lung. After ruling out malignancy, the diagnosis of ABPA was established based on Rosenberg?Patterson criteria. Treatment with oral steroids for 6 months in tapering doses lead to clinical and radiological improvement and decrease in IgE levels.

Keywords: Allergic bronchopulmonary aspergillosis, Malignancy, Rosenberg Patterson Criteria, Fibreoptic Bronchoscopy, IgE levels

Edition: Volume 12 Issue 10, October 2023,

Pages: 1980 - 1981