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Research Paper | Nursing | India | Volume 11 Issue 9, September 2022

Effectiveness of Chlorhexidine Mouthwash Prophylaxis for Prevention of Ventilator - Associated Pneumonia among Children Receiving Mechanical Ventilation in Paediatric Intensive Care Unit at KGMU, Lucknow, U. P.

Sanjay Kumar Sahu

Abstract: Ventilator associated pneumonia (VAP) is common problem among mechanically ventilated patients. However improvements in oral hygiene in these patients may prevent ventilator - associated pneumonia. The goal of this study was to determine the efficacy of 0.12% chlorhexidine gluconate mouth care to prevent the VAP among mechanically patients admitted in PICU. A randomized control trial was carried out on 70 patients, where equal number of patients randomized in experimental (35 patients) and control group 35 subjects. Study was conducted to assess the efficacy of 0.12% chlorhexidine gluconate mouth care in prevention of VAP among mechanically ventilated patients. Study found that mouth care with 0.12% chlorhexidine twice daily was significantly effective in prevention of VAP among mechanically ventilated patients as compared to conventional method of mouth care without any significant adverse event (p<0.05). furthermore, it found that increased duration of mechanical ventilation escalates the risk of VAP, however, chlorhexidine mouth care was consistently effective with even longer duration of mechanical ventilation (day 7 p<0.05). Mouth care twice daily with 0.12% chlorhexidine is significantly effective in prevention of VAP among mechanically ventilated patients. Therefore, it is recommended to provide mouth care twice daily with 0.12% chlorhexidine to mechanically ventilated patients for prevention of VAP.

Keywords: Chlorhexidine mouthwash prophylaxis, ICU, Prevention, Ventilator associated pneumonia, children, Mechanical Ventilation

Edition: Volume 11 Issue 9, September 2022,

Pages: 511 - 513