Evaluation of Anaemia in Type 2 Diabetes Mellitus Patients with Special Reference to Vitamin B12 Deficiency
Abstract: Background: Anemia is prevalent in patients with diabetes. It predicts the progression of diabetic complications. 1Vitamin B12 deficiency is also a potential comorbidity in diabetes mellitus. 2 The aim of this study was to evaluate anaemia in patients with type 2 diabetes mellitus with normal renal function with special reference to vitamin B12 deficiency. Methods: This study was an observational study conducted where 190 cases > 13 years of age with type 2 diabetes mellitus having eGFR >60 ml/min; serum creatinine 1000mg, duration of metformin use >5 years, hypertension, dyslipidemia, poor glycemic control, microalbuminuria were found to be statistically significant risk factors. The prevalence of diabetic complications was higher in patients with anaemia. The prevalence of Vitamin B12 deficiency was 17.36% being an independent risk factor for anaemia. (p=0.113; OR=1.9). Conclusion: Anaemia is prevalent in type 2 diabetics even before the onset of renal impairment with higher prevalence of complications (microvascular mainly studied here) which increased with increasing severity of anaemia. Vitamin B12 deficiency is prevalent in diabetics with anaemia.
Keywords: Type 2 Diabetes Mellitus, Anaemia, Vitamin B12 deficiency
How to Cite?: Dr. Krithika .K, Dr. Subha Lakshmi Das, "Evaluation of Anaemia in Type 2 Diabetes Mellitus Patients with Special Reference to Vitamin B12 Deficiency", Volume 11 Issue 5, May 2022, International Journal of Science and Research (IJSR), Pages: 1705-1709, https://www.ijsr.net/getabstract.php?paperid=SR22518161420, DOI: https://dx.doi.org/10.21275/SR22518161420