A Comparative Study of Oral Nifedipine and Oral Labetalol in the Treatment of Pregnancy-Induced Hypertension
Abstract: Background: Hypertensive disorders of pregnancy impact on maternal and neonatal mortality and morbidity. Various anti-hypertensive drugs have been used such as methyldopa, nifedipine, labetalol and hydralazine for treatment of pre-eclampsia. Aim: To compare the efficacy and safety of oral Labetalol with oral Nifedipine in the management of pre-eclampsia. Methodology: This is a longitudinal study in which 100 pregnant women diagnosed with pregnancy induced hypertension in severe pre-eclampsia in labour room were enrolled. Patients were given Nifedipine 10mg stat orally and BP was checked every 5min and repeat dosing was considered after 15-20min. Similar method was followed for oral Labetalol but with a dose of 100mg and BP was checked every 5min till target BP was achieved. Patients of both the groups were observed in the hospital till delivery. Results: In the present study there is a significant decline rate in diastolic BP in both the groups (p
Keywords: Labetalol, Nifedipine, Hypertension, Pregnancy, Pre-eclampsia
How to Cite?: Acharya Tonima, Pradhan Subhrasmita, Das Rashmi, Pandey Sachchidanand, "A Comparative Study of Oral Nifedipine and Oral Labetalol in the Treatment of Pregnancy-Induced Hypertension", Volume 11 Issue 12, December 2022, International Journal of Science and Research (IJSR), Pages: 461-464, https://www.ijsr.net/getabstract.php?paperid=SR221208134207, DOI: https://dx.doi.org/10.21275/SR221208134207