Downloads: 52 | Views: 418 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper | Medical Microbiology | Egypt | Volume 10 Issue 3, March 2021 | Popularity: 6.7 / 10
Synergistic Antimicrobial Effect of Egyptian Honey with Antibiotics and Its Capability to Restore MRSA Sensitive to Oxacillin
Abdul-Hafeez M. M., Hamouda .S .M, Abd El Rahman M. F.
Abstract: Since some types of honey interact synergistically at sub-lethal (sub MIC) concentrations with antibiotics, the work tested this activity of six Egyptian honey brands; three of potent (fennel, 2 of anise & black seed) as well as three of fair antimicrobial activity (multi-floral) against two G-ve and two G+ve multi drug resistant bacterial strains [E. coli AUMC B-243, Klebsiella pneumonia AUMC B-257 and Strept. agalactiae AUMC B-253 and methicillin resistant Staphylococcus aureus (MRSA)] using agar dilution method. The four bacterial strains had high resistance index (RI) ranging (0.18 – 0.73). All tested honey brands had different potencies of antimicrobial activity against all bacterial strains with MICs values (6-15 %), where the best overall MIC was with the use of anise & black seed II (8.5 %) followed by fennel (9.5 %). Either of potent or fair antimicrobial honey brands showed synergistic action with different antimicrobial agents against MRSA with synergistic index (SI) ranged from 0.17 up to 0.39, where the best overall SI of each honey brand against the tested antimicrobial agents was with the use of anise & black seed I (0.39) followed by fennel (0.37). None of the tested honey types showed bactericidal action and all had bacteriostatic activity but the interesting wonderful observation as that all tested Egyptian honey brands (either with of potent or fair activity) restored MRSA (methicillin resistant Staphylococcus aureus) sensitive to Oxacillin being MESSA (methicillin sensitive Staphylococcus aureus). The study concluded that all six tested honey either of potent or fair antimicrobial activity honey brands had variable synergistic activity with antibiotics against MRSA and restored it sensitive to Oxacillin. Keywords: Egyptian honey, antimicrobial, MRSA, synergism
Keywords: Egyptian honey, antimicrobial, MRSA, synergism
Edition: Volume 10 Issue 3, March 2021
Pages: 1389 - 1395
DOI: https://www.doi.org/10.21275/SR21313001535
Make Sure to Disable the Pop-Up Blocker of Web Browser
Similar Articles
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Student Project, Medical Microbiology, Kenya, Volume 11 Issue 8, August 2022
Pages: 762 - 765Occurrence of Post-Surgical Wound Infections, Bacterial Isolates, and their Susceptibility to Commonly Used Antibiotics at Kenyatta National Hospital, Kenya
Magdaline Burugu, Andrew Nyerere, Susan Odera, Lameck Ontweka
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medical Microbiology, India, Volume 11 Issue 12, December 2022
Pages: 666 - 669Prevalence of Acinetobacter spp in ICU at Tertiary Care Hospital, VIMSAR, BURLA
Dr. Ranjan Kumar Samal, Dr Sudipta Kumar Ram
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medical Microbiology, India, Volume 12 Issue 9, September 2023
Pages: 1917 - 1922Antimicrobial Resistance: Unraveling Mechanisms, Impacts, and Novel Intervention Strategies
Saket Gupta, Sagar Gupta, Shivam Agarwal
Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Analysis Study Research Paper, Medical Microbiology, India, Volume 12 Issue 12, December 2023
Pages: 1664 - 1667Changing Pattern of Antibiotic Profile of Gram Negative Blood Stream Infections in NICU in a Tertiary Care Hospital
Dr. Gurpreet Kaur, Dr. Kamaldeep Singh, Dr. Loveena Oberoi, Dr. Tavishi Oberoi
Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙2
Research Paper, Medical Microbiology, India, Volume 14 Issue 1, January 2025
Pages: 948 - 951Recent Trends in LSCS Surgical Site Infections and Therapeutic Strategies
Dr. Winston Rose Cr, Dr. Deepa S, Dr. Amrutha Kumari B