International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 54 | Views: 197

Research Paper | Anaesthesiology | India | Volume 10 Issue 3, March 2021 | Rating: 6.6 / 10


The Comparison of the Effects of Dexmedetomidine and Magnesium Sulphate in Endoscopic Transnasal Transsphenoidal Resection of Pituitary Adenoma

Dr. Khushbu Umeshbhai Dhameliya | Dr. Monal Ramani | Dr. Manoj Kumar M [2] | Dr. Nidhi Jayeshbhai Sejpal


Abstract: Transsphenoidal resection of the pituitary tumours involves wide fluctuations in haemodynamic parameters such as hypertension and tachycardia due to local adrenaline infiltration, during nasal speculum insertion and during sphenoid resection. It is challenging for anaesthetist to provide bloodless field, heamodynamiac stability, surgical approach. In this study we compared the effects of dexmedetomidine and magnesium sulphate on the adequacy of hypotensive anaesthesia to produce bloodless field and decreasing the bloodloss in adult patients undergoing transsphenoidal resection of pituitary tumours. Using Boezaart surgical field grading and surgeons satisfaction score surgical field was graded. From our results we conclude that dexmedetomidine has advantage of causing controlled hypotension and reduction in heart rate with minimal blood loss compared to magnesium sulphate.


Keywords: dexmedetomidine, magnesium sulphate, bloodless field, hemodynamic stability, controlled hypotension


Edition: Volume 10 Issue 3, March 2021,


Pages: 80 - 83


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