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Case Report | Radiology and Medical Imaging Sciences | Volume 15 Issue 8, August 2026 | Pages: 1337 - 1339 | India
Sinonasal Teratocarcinosarcoma with Orbital and Anterior Skull Base Involvement: A Contrast-Enhanced CT-Based Case Report
Abstract: Background: Sinonasal teratocarcinosarcoma (SNTCS) is a rare and aggressive malignant tumour of the sinonasal tract (SNT) with a prevalence of less than 1% of SNT malignancies. The diagnosis may be delayed since it is a heterogeneous histopathological lesion with non-specific symptoms. Imaging has an important role and adds significant value when used for determining the extent of the disease and directing management. Case Presentation: There was a 53-year-old man who had been having progressive bilateral nasal obstruction and epistaxis for 3 months. Computed tomography (CT) revealed a soft tissue-density mass lesion in the right nasal cavity that had heterogeneous enhancement. It severely damaged the sinonasal skeleton, specifically the lamina papyracea, orbital floor, sphenoid bone, and anterior skull base. The lesion involved the orbit and had extra-axial intracranial extension. Histopathological diagnosis showed sinonasal teratocarcinosarcoma. Extensive local invasion of the lesion was noted, and management was a combination of optimal chemotherapy and radiation therapy with external beam radiotherapy (EBRT) and specific drugs- paclitaxel and carboplatin. Case Summary: This case illustrates the typical CT appearance of SNTCS, the extent of the tumour and the use of contrast-enhanced CT to assist in the management.
Keywords: Sinonasal teratocarcinosarcoma, Contrast-enhanced computed tomography, Sinonasal malignancy, Skull base invasion, Orbital invasion
How to Cite?: Dr. Pallab Biswas, Dr. Hitesh Rajpura, "Sinonasal Teratocarcinosarcoma with Orbital and Anterior Skull Base Involvement: A Contrast-Enhanced CT-Based Case Report", Volume 15 Issue 8, August 2026, International Journal of Science and Research (IJSR), Pages: 1337-1339, https://www.ijsr.net/getabstract.php?paperid=MR26818140445, DOI: https://dx.doi.org/10.21275/MR26818140445