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Informative Article | Dentistry | Volume 15 Issue 5, May 2026 | Pages: 1455 - 1461 | India
Clinical Efficacy and Osseointegration of Bioactive Surface versus SLA Surface Dental Implants in Patients Requiring Implant Therapy: A Systematic Review and Meta-Analysis
Abstract: Background: Surface characteristics of dental implants significantly influence clinical success and osseointegration. Bioactive surfaces are hypothesised to enhance osseointegration more effectively than conventional sandblasted, large-grit, acid-etched (SLA) surfaces. Objective: To systematically compare the clinical efficacy and implant stability of bioactive versus SLA surface implants in patients undergoing dental implant therapy. Methods: This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251024387). Randomised controlled trials (RCTs) comparing bioactive and SLA surface implants with reported implant stability quotient (ISQ) values were included. PubMed, Cochrane CENTRAL, and Web of Science were searched up to June 2024. Meta-analyses employed both fixed- and random-effects models. Risk of bias was evaluated using the Cochrane RoB 2.0 tool; heterogeneity and publication bias were assessed using I2 statistics, Egger's test, and Begg's test. Results: Ten RCTs involving 468 implants (232 bioactive, 236 SLA) were analysed. At baseline, bioactive surfaces demonstrated significantly higher stability (SMD = 0.365; 95% CI: 0.026-0.704; p = 0.035). At follow-up (6-12 weeks), this advantage increased markedly (SMD = 0.880; 95% CI: 0.372-1.388; p = 0.001). Heterogeneity was moderate to high (I2 = 69.42%-85.19%). No significant publication bias was detected. Conclusion: Bioactive implant surfaces are associated with superior implant stability, particularly during early healing. These findings support their clinical use to enhance osseointegration in patients requiring dental implant therapy.
Keywords: bioactive surface, SLA surface, dental implants, osseointegration, implant stability quotient, systematic review, meta-analysis
How to Cite?: Shivani Jani, Mishal Shah, Amit Benjamin, Shreya Rawal, "Clinical Efficacy and Osseointegration of Bioactive Surface versus SLA Surface Dental Implants in Patients Requiring Implant Therapy: A Systematic Review and Meta-Analysis", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 1455-1461, https://www.ijsr.net/getabstract.php?paperid=MR26520142302, DOI: https://dx.dx.doi.org/10.21275/MR26520142302