Isolated Calvarial Metastasis from Follicular Thyroid Carcinoma: A Diagnostic and Surgical Challenge
Abstract: Follicular Thyroid Carcinoma is characterized by hematogenous spread and has a higher propensity for skeletal metastasis compared to other differentiated thyroid carcinomas. Calvarial metastasis, however, remains an exceptionally rare presentation and may occur years after definitive treatment. We report a rare case of isolated calvarial metastasis in a 62-year-old female previously treated for follicular thyroid carcinoma with total thyroidectomy and RAI therapy 2.5 years earlier. She presented with a progressively enlarging right parieto-temporo-occipital scalp swelling associated with headache and intermittent blurring of vision. Imaging revealed a solitary osteolytic calvarial lesion, and histopathological examination confirmed metastatic follicular thyroid carcinoma. This case highlights the indolent yet metastatic potential of follicular thyroid carcinoma and emphasizes the importance of long-term surveillance in treated patients. Reporting such rare presentations may improve clinical awareness, facilitate early recognition of unusual metastatic sites, and support timely multidisciplinary management for improved patient outcomes.
Keywords: Follicular thyroid carcinoma, Calvarial metastasis, Skeletal metastasis, Thyroid cancer recurrence, long term surveillance
How to Cite?: Dr. Rajshekhar C Jaka, Dr. Sushma Biradar, Dr. Krishna Shah, Dr. Venkatakrishna BR, "Isolated Calvarial Metastasis from Follicular Thyroid Carcinoma: A Diagnostic and Surgical Challenge", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 1080-1083, https://www.ijsr.net/getabstract.php?paperid=MR26515222131, DOI: https://dx.doi.org/10.21275/MR26515222131