Prevalence of Metabolic Syndrome and Its Association with Disease Severity in Patients with Chronic Obstructive Pulmonary Disease

Dr. V. Santhosh Kumar, Dr. P. Maneesha, Dr. M. Venu

Abstract: Background: Chronic Obstructive Pulmonary Disease (COPD) is a systemic inflammatory disease frequently associated with comorbidities like Metabolic Syndrome (MS), which may worsen clinical outcomes. Aim: To determine prevalence of MS in COPD patients and its association with severity of Airflow obstruction. Objective: To determine the prevalence of MS in COPD patients and assess its relationship with disease severity based on GOLD spirometric classification. Methods: This cross-sectional study was conducted on 100 spirometry-confirmed COPD patients at a teritiary care centre in a semi urban area, from September 2023 to February 2024. MS was diagnosed using modified NCEP ATP III criteria. Demographic, clinical, and biochemical profiles were collected and analyzed. Results: MS was present in 48% of patients, with significantly higher prevalence in females (62.5%) than males (41.1%). Most MS patients belonged to GOLD stage II. Though FEV? was slightly higher in MS patients, the difference was not statistically significant. Conclusion: Metabolic Syndrome is prevalent among COPD patients, especially in women and those with moderate disease. Routine screening and early intervention may improve outcomes.

Keywords: COPD, Metabolic Syndrome, GOLD Classification, Spirometry, Comorbidities

How to Cite?: Dr. V. Santhosh Kumar, Dr. P. Maneesha, Dr. M. Venu, "Prevalence of Metabolic Syndrome and Its Association with Disease Severity in Patients with Chronic Obstructive Pulmonary Disease", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 411-413, https://www.ijsr.net/getabstract.php?paperid=MR25806100458, DOI: https://dx.doi.org/10.21275/MR25806100458