Study of Outcomes of Splenectomy and Study of Complications Ligament First Approach vs Hilum First Approach

Dr. Bhargavi Boppana, Dr. Meghraj Jayantilal Chawada, Dr. Shobha Nisale, Dr. Sumit Chavhan

Abstract: Thalassemia major is a severe hemoglobinopathy requiring regular blood transfusions, leading to iron overload and splenomegaly. Splenectomy is often performed to reduce transfusion burden and improve hematological parameters. This study evaluates the impact of splenectomy on hemoglobin levels, iron overload, transfusion frequency, and quality of life among patients at a tertiary care center. A comparative analysis of 50 cases from 2023?2025 was conducted, assessing pre- and post-splenectomy clinical parameters. Thalassemia major patients often develop splenomegaly and require splenectomy, which carries risks like splenic artery aneurysm, splenic vessels fistula, GI discomfort and hemorrhage. This study evaluates post-splenectomy complications alongside hematological outcomes in a tertiary care setting.

Keywords: Splenectomy, Thalassemia Major, Hemoglobin, Iron Overload, Blood Transfusion, Ligament First Approach, Hilum First approach

How to Cite?: Dr. Bhargavi Boppana, Dr. Meghraj Jayantilal Chawada, Dr. Shobha Nisale, Dr. Sumit Chavhan, "Study of Outcomes of Splenectomy and Study of Complications Ligament First Approach vs Hilum First Approach", Volume 14 Issue 8, August 2025, International Journal of Science and Research (IJSR), Pages: 334-339, https://www.ijsr.net/getabstract.php?paperid=MR25804185055, DOI: https://dx.doi.org/10.21275/MR25804185055