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Research Paper | Medical Surgical | Volume 14 Issue 4, April 2025 | Pages: 2482 - 2484 | India
Role of Arterial Blood Levels of Serum Lactate as a Biomarker of Intestinal Ischemia in Patients of Intestinal Obstruction
Abstract: Background: Intestinal obstruction is a common surgical emergency. Strangulated obstruction may result in bowel ischemia, leading to significant morbidity and mortality. Early identification of ischemia is critical. This study evaluates arterial blood levels of serum lactate as a biomarker for predicting intestinal ischemia in patients presenting with intestinal obstruction. Methods: A cross - sectional observational study was conducted over one year on 60 patients presenting with clinical features of intestinal obstruction requiring surgery. Serum lactate levels were measured preoperatively and 24 hours postoperatively. The association of lactate levels with intraoperative findings of bowel ischemia was analyzed using ROC curve analysis. Results: Bowel ischemia was identified in 16.7% (10/60) of cases. Mean preoperative serum lactate was significantly higher in patients with bowel ischemia (3.25 ? 1.46 mmol/L) compared to those without (1.22 ? 0.41 mmol/L, p
Keywords: Serum lactate, Intestinal obstruction, Intestinal ischemia, Biomarker, Surgery, Bowel strangulation
How to Cite?: Dr. Ravikant Bhardwaj, Dr. Surabhi Sharma, "Role of Arterial Blood Levels of Serum Lactate as a Biomarker of Intestinal Ischemia in Patients of Intestinal Obstruction", Volume 14 Issue 4, April 2025, International Journal of Science and Research (IJSR), Pages: 2482-2484, https://www.ijsr.net/getabstract.php?paperid=MR25501140011, DOI: https://dx.doi.org/10.21275/MR25501140011