A Study on Significance of Blood Lactate Levels and Lactate Clearance in the Prognosis of Polytrauma Patients
Abstract: Introduction: Polytrauma involves injuries across multiple body regions, often life-threatening, and remains a major cause of mortality, especially among individuals aged 15?29. Identifying markers of hypoperfusion is crucial in the management of such patients. Serum lactate, a byproduct of anaerobic metabolism, has been widely studied as an indicator of tissue hypoxia. This study evaluates the prognostic value of serial lactate clearance in polytrauma patients. Methods: A prospective observational study was conducted on 100 polytrauma patients (ISS >16) admitted to the Emergency Department at Alluri Sitarama Raju Academy of Medical Sciences between July 2022 and June 2024. Lactate levels were recorded at admission, 2, 24, and 48 hours, and clearance was calculated at each interval. Patients were followed up for 30 days. Statistical analysis was performed using the Mann-Whitney test, with a significance level set at p
Keywords: Polytrauma, lactate clearance, hypoperfusion, trauma prognosis, emergency care, serum lactate, injury severity score
How to Cite?: Dr. Gaali Sai Ravi Teja Krishna Reddy, Dr. Sarath Babu Gillellamudi, Dr. K. Suhas, "A Study on Significance of Blood Lactate Levels and Lactate Clearance in the Prognosis of Polytrauma Patients", Volume 14 Issue 4, April 2025, International Journal of Science and Research (IJSR), Pages: 1370-1372, https://www.ijsr.net/getabstract.php?paperid=MR25418095439, DOI: https://dx.doi.org/10.21275/MR25418095439