A Clinical Evaluation of Serum Vitamin D Levels in Patients with Vitiligo

Dr. Prathyusha Prabhakar

Abstract: Background: The autoimmune hypothesis highlights the potential role of low serum vitamin D levels in the pathogenesis of vitiligo. This study aimed to determine the association between serum vitamin D levels and vitiligo. Fifty adult vitiligo patients and fifty healthy controls were included in this case - control study. Serum vitamin D levels were measured and analyzed statistically. The findings revealed significantly lower serum vitamin D levels in vitiligo patients, with variations observed based on disease severity and extent. Results: There was a significant difference in mean vitamin D3 levels among vitiligo patients with localized, generalized, and universal disease involvement (p < 0.001). These results suggest that vitamin D deficiency may play a role in vitiligo progression, emphasizing its potential as a therapeutic target.

Keywords: Vitamin D3, vitiligo, melanocytes, autoimmune disorders, dermatology

How to Cite?: Dr. Prathyusha Prabhakar, "A Clinical Evaluation of Serum Vitamin D Levels in Patients with Vitiligo", Volume 14 Issue 1, January 2025, International Journal of Science and Research (IJSR), Pages: 449-452, https://www.ijsr.net/getabstract.php?paperid=MR25110094339, DOI: https://dx.doi.org/10.21275/MR25110094339