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Analysis Study Research Paper | Cardiology Science | India | Volume 12 Issue 7, July 2023
Left Ventricular Functions in Patients with Chronic Kidney Disease
Dr. Basavaraj H Mali | Dr. Tejaswini K
Abstract: Introduction: Chronic kidney disease (CKD) encompasses a spectrum of pathophysiological process associated with abnormal kidney function and a progressive decline in glomerular filtration rate1. It is a global health concern. CKD has been the 12th leading cause of mortality and 17th leading cause of disability2. Leading categories of etiologies for CKD are diabetic nephropathy, glomerulonephritis and hypertension. Most patients with CKD succumb to cardiovascular disease before ever reaching stage 5 CKD. A large cohort study of patients with CKD stages 2 to 4 showed that death was seen more often than progression to kidney failure in all stages of CKD. Hence most patients in the earlier stages of CKD do not progress to kidney failure because of mortality caused due to cardiovascular disease. Materials and method: This was a cross sectional study carried out with 100 patients who were already diagnosed to have Chronic Kidney Disease. Cardiac function was assessed using echocardiography and left ventricular function in the form of left ventricular ejection fraction was measured. It was compared among different stages of CKD. Results: The study documented a significant reduction in the left ventricular function in patients with CKD, It was observed that 60% had systolic dysfunction with left ventricular ejection fraction less than 50%. Conclusion: This study was mainly undertaken to study Echocardiographic changes in CKD patients. This study had shown that left ventricular hypertrophy was present in significant number of patients with Chronic Kidney Disease. This study also showed that LV systolic dysfunction was significant in CKD patients. Regular Echocardiographic evaluation of CKD patients forms an important tool in early identification and prevention of cardiovascular complications associated with Chronic Kidney Disease.
Keywords: Chronic Kidney Disease; Diabetes Mellitus; Left Ventricular Hypertrophy; Diastolic Dysfunction; Echocardiography
Edition: Volume 12 Issue 7, July 2023,
Pages: 1130 - 1132