Downloads: 3 | Views: 107 | Weekly Hits: ⮙1 | Monthly Hits: ⮙3
Analysis Study Research Paper | Radiology and Medical Imaging Sciences | India | Volume 12 Issue 6, June 2023
Role of Conventional and Diffusion Weighted MRI in Evaluation of Endometrial Lesions
Dr. Sunita [26] | Dr. Sunil Kumar Agrawal | Dr. Suresh Chandra Gupta | Dr Nalin Dhadhich | Dr. Vineet Mishra
Abstract: Purpose: In clinically suspected cases of endometrial lesions to see the role of MRI in evaluation of morphology of endometrial lesions and to compare the findings in benign and malignant endometrial lesions. To assess the stage of disease in patients with endometrial carcinoma using MRI and compare it with operative staging wherever available. Material & method: A prospective study of 45 patients who were referred to radiology department with suspicion of endometrial lesion. The study was conducted after getting approval from institution?s ethical committee and after obtaining written informed consent from the patients. The study was conducted from period of March 2021 to Oct 2022 in Department of Radio-diagnosis referred from the Department of Obstetrics and Gynaecology and medical & surgical oncology for contrast MRI of lower abdomen and pelvis using-Seimens MRI 3 Tesla. Observation: Out of 45 patients, 20 patients had benign lesions and 25 patients had malignant lesions. Mean age of patients with benign lesions was 43.60 years, whereas mean age of patients presenting with malignant lesions was 57.04 years. The spectrum of benign lesions included endometrial polyp (n=6), fibroids (n=6), endometrial hyperplasia (n=3), secretory endometrium (n=1), endometritis (n=1), endometrial synechiae (n=2) and hydatidiform mole (n=1).3 cases were diagnosed as having endometrial hyperplasia seen as diffuse endometrial thickening with smooth margins and showing hypointense signal on T1 WI and brightly hyperintense on T2WI. One patient was diagnosed to have hydatidiform mole. One patient was diagnosed to have endometritis.24/25 (96%) patients had endometrial carcinoma. The most common pathology was endometrial carcinoma comprising 24/ 25 cases (96%). Mean thickness of the lesion was 28.84mm. T2 intermediate hyperintense signal of tumor (96% malignant lesions) and irregularity of tumor/ endo myometrial junction (92 % malignant lesion) were significantly more common in malignant lesions (p <0.001). The MR findings of local invasion were concordant with histopathological examination in 18 (85.7 %) patients by combined T2WI+DWI+CE imaging. Conclusions: A newer functional MR techniques like diffusion weighted MRI using presence of diffusion restriction, ADC values can add to conventional MR imaging. MR with newer techniques can aid in preoperative carcinoma endometrium staging with good accuracy, for better management and prognosis of the patients.
Keywords: MRI, Endometrial Lesions
Edition: Volume 12 Issue 6, June 2023,
Pages: 387 - 397