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Dissertation Chapters | Obstetrics and Gynecology | India | Volume 12 Issue 5, May 2023
Prospective Observational Study of Magnesium Sulphate as Pritchard Regimen in Severe Pre-Eclampsia and Eclampsia
Dr. Madhukar Gajanan Borkar | Dr. Bhaskar Murthy
Abstract: Background: Pre?eclampsia / eclampsia is a multisystem disorder of pregnancy that carries a high risk of maternal and perinatal mortality and morbidity worldwide. Magnesium sulphate is the anticonvulsant of choice in prevention and control of eclamptic convulsions. Pritchard's regimen is the most popular time-tested regimen used. Hence the present study was undertaken to study the magnesium sulphate as Pritchard regimen in severe pre-eclampsia and eclampsia. Method: A total of 111 pregnant women coming to labour room included in the study if their blood pressure was>140 mmHg systolic (SBP) OR >90 mmHg diastolic (DBP) on at least two occasions on at least 4 hours apart. Results: Out of 111 patients 17 (15.32%) were antepartum eclampsia, 90 (81.08%) belong to impending eclampsia and only 4(3.60%) were postpartum eclampsia. Maximum patients 66(59.46%) were primigravida, followed by multigravida 4 (36.94%) and 4 (3.60%) were postdelivery. The gestational age was between 27-41 weeks with mean of 35.44?3.99 weeks. Majority of patients belong to gestational age between 33-38 weeks (56; 50.45%). The mean systolic blood pressure was 161.53?16.35 mmHg and the mean diastolic blood pressure was 108?7.80 mmHg was noted on admission.Out of 111 patients 64 (57.66%) was delivered by cesarean section and 47 (42.34%) were delivered by vaginal route.The mean duration of stay was 10.60?4.71 days. Conclusion: Proper antenatal care, improved socio-economic status and intensivemanagement will largely reduce the incidence of eclampsia.Magnesium sulphate is the most preferable drug for prevention and treatment of eclamptic patients.
Keywords: Pre?eclampsia, Eclampsia, Magnesium sulphate, Anticonvulsant, Pritchard's regimen
Edition: Volume 12 Issue 5, May 2023,
Pages: 112 - 115