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Case Studies | Ophthalmology | India | Volume 12 Issue 12, December 2023

Branch Retinal Vein Occlusion and Serum Homocystein Level

Dr. Suvarna Kalapad | Dr. Ajay Tammewar

Abstract: This article delves into the intricate relationship between elevated homocysteine levels and Branch Retinal Vein Occlusion BRVO, a prevalent retinal vascular disease. Focusing on a study of 10 patients aged between 50 and 70 years, diagnosed with BRVO, it evaluates the implications of homocysteine in the pathogenesis and management of this condition. The study highlights how systemic conditions like hypertension, diabetes, and hyperlipidemia contribute to arteriosclerosis, thereby affecting BRVO development. It also examines the impact of homocysteine on endothelial cell damage and Vascular Endothelial Growth Factor VEGF activation, and the role of vitamins like folate, B6, and B12 in mitigating homocysteine levels. The findings from the patient group, including variations in visual outcomes and the effectiveness of treatments like anti-VEGF injections and vitamin supplementation, offer critical insights into the potential for therapeutic interventions in managing BRVO. This comprehensive analysis underscores the need for further research to establish a definitive link between homocysteine levels and retinal vein occlusions, potentially paving the way for innovative treatment strategies.

Keywords: Retinal Vein Occlusion, Homocysteine, BRVO, Endothelial Damage, Vitamin Supplementation

Edition: Volume 12 Issue 12, December 2023,

Pages: 1895 - 1897