Evaluation of Dexmedetomidine in Quality of Extubation Response in Smokers undergoing Surgeries under General Anaesthesia

Vivek Chaudhary

Abstract: Introduction: Smokers are one of the at-risk group of patients prone for developing complications during extubation. Objective: Evaluation of dexmedetomidine in quality of extubation response in smokers undergoing surgeries under general anaesthesia. Study design: Prospective randomized study. Method: Sixty patients of ASA physical status I and II were enrolled in the study and dividedinto2groupsof30each. Group A included 30 patients who received 0.5 ?g/kg of dexmedetomidine in normal saline (Total volume 10 ml). Group B included 30 patients who received 0.75 ?g/kg of dexmedetomidine in normal saline (Total volume 10 ml). Results: Both groups were comparable in terms of age, sex, ASA grade, smoking index, and duration of surgery (P>0.05). Intra-operative hemodynamic variables before start of infusion were comparable in both groups. In the present study, quality of extubation was significantly poorer in group A in comparison to group B (P=0.001). Conclusion: Dexmedetomidine with dose of 0.75 ?g/kg is the best dose for attenuation of extubation response in current smoker patients undergoing major surgery.

Keywords: dexmedetomidine, extubation response

How to Cite?: Vivek Chaudhary, "Evaluation of Dexmedetomidine in Quality of Extubation Response in Smokers undergoing Surgeries under General Anaesthesia", Volume 11 Issue 1, January 2022, International Journal of Science and Research (IJSR), Pages: 1089-1091, https://www.ijsr.net/getabstract.php?paperid=MR22119202943, DOI: https://dx.doi.org/10.21275/MR22119202943