Study of the Variation of Neuroglobinemia and Cytoglobinemia in Homozygous Sickle Cell Subjects
Abstract: SUMMARY Introduction: The data on the variation of neuroglobinemia (CmNgb) and cytoglobinemia (CmCygb) in sickle cell disease (SCD) are unknow. Objective: To determine in the sickle cell subject, the variations of CmNgb and CmCygb, and to study the relationships between these variations and the pathophysiological factors of sickle cell disease. Population and methods: The study involved 30 inter critical sickle cell patients (HbSS-), 20 in crisis (HbSS+) and 36 controls (HbAA). The CmNgb and CmCygb (ng/ml), as well as markers of hypoxia, inflammation, hemolysis and ischemia of the nervous system (NS) were determined. The comparison of variables between different groups, as well as their relationships was analysed (p
Keywords: Neuroglobin - Cytoglobin - Sickle Cell Disease - Pathophysiology
How to Cite?: Nnang Essone JF, Mba Aki Angue TH, Diaw M, Nkiema R, Dibanganga J, Anyunzoghe E, Ekegue N, Bitegue Methe L, Edzang L, Belmalih M, Igala M, Mba C, Ovono Abessolo F, Samb A, "Study of the Variation of Neuroglobinemia and Cytoglobinemia in Homozygous Sickle Cell Subjects", Volume 9 Issue 2, February 2020, International Journal of Science and Research (IJSR), Pages: 535-551, https://www.ijsr.net/getabstract.php?paperid=ART20204499, DOI: https://dx.doi.org/10.21275/ART20204499