In Vivo Antitussive Activity of Chrysophyllum welwitschii against Ammonia Liquor-Induced Cough in Rats
Abstract: The study was carried out to evaluate antitussive activity of the aqueous and ethanolic extracts from leaves of Chrysophyllum welwitschii (CHRYSOW) in laboratory animals. The present study was designed to observe pharmacological activities of the leaves extract of the plant Chrysophyllum welwitschii. Antitussive activity was performed by ammonia liquor-induced cough reflex rats. Analgesic and antipyretic activities were evaluated by the dose of 250 and 500 mg/kg body weight. The aqueous and ethanolic extracts of CHRYSOW (500 mg/kg) exhibited significant antitussive activity i. e.77.82 % and 65.21 % respectively, but lower dose (250 mg/kg) of these showed less activity i. e.31.70 % and 22.80 % respectively, inhibition in ammonia liquor induced cough (P
Keywords: cough, antitussive activity, Chrysophyllum welwitschii, dextromethorphan
How to Cite?: Agnero S. M., Pakora G. A., Yeo Dodehe, N'Guessan J. D., Djaman A. J., "In Vivo Antitussive Activity of Chrysophyllum welwitschii against Ammonia Liquor-Induced Cough in Rats", Volume 7 Issue 12, December 2018, International Journal of Science and Research (IJSR), Pages: 1172-11174, https://www.ijsr.net/getabstract.php?paperid=ART20192934, DOI: https://dx.doi.org/10.21275/ART20192934