Assessment of Interleukin-1? and Myeloperoxidase Levels around Implants versus Natural Teeth with the Impact of Aloe Vera
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 120 | Views: 333

Research Paper | Dental Science | Iraq | Volume 6 Issue 6, June 2017 | Popularity: 6.9 / 10


     

Assessment of Interleukin-1? and Myeloperoxidase Levels around Implants versus Natural Teeth with the Impact of Aloe Vera

Ahlam T. Mohammed, Nadia Aftan AL-Rawi, Batool Hassan AL-Ghurabi


Abstract: Background It is essential that peri-implant and periodontal sites are studied to contribute comparison data for investigations that are dealing with diseased sites. The objective of this study was to compare the expression of host-derived markers interleukin-1 (IL-1) and myeloperoxidase (MPO) in peri-implant sulcular fluid (PISF) with the gingival crevicular fluid (GCF) of contralateral natural teeth and to investigate the anti-inflammatory effect of Aloe vera gel on these biomarkers. Materials and Methods 20 subjects aged 25- 45 year who have one clinically stable titanium implant carrying a full ceramic crown and one contralateral natural tooth were enrolled in a split-mouth study. Clinical parameters were measured including Plaque index (Pl I), , Gingival Index (GI), Probing depth (PD). PISF and GCF were collected and the levels of interleukin-1 and myeloperoxidase were determined using ELISA technique at baseline and 2 weeks after application of Aloe vera gel. Results IL-1 level in PISF was higher than in GCF with no significant difference (p > 0.05) while MPO concentration was higher in PISF than in GCF with highly significantly difference (P< 0.01). Positive correlations were found between the levels of IL-1 and MPO with clinical parameters (Pl I, GI and PD). After application of Aloe vera gel there was a reduction in the levels of both IL-1 and MPO with no significant difference (p > 0.05) for IL-1 and highly significantly difference (P< 0.01) for MPO in implants group only. ConclusionsDifferential expression of specific biomarkers in GCF versus their levels in PISF is important information prior to establishing PISF as a diagnostic fluid to monitor peri-implant health. Inflammatory mediators production were higher around implants than teeth and Aloe vera gel has anti-inflammatory effect on peri-implant tissue.


Keywords: Peri-implant sulcular fluid, interleukin-1, myeloperoxidase, Aloe vera


Edition: Volume 6 Issue 6, June 2017


Pages: 1701 - 1705



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!
Ahlam T. Mohammed, Nadia Aftan AL-Rawi, Batool Hassan AL-Ghurabi, "Assessment of Interleukin-1? and Myeloperoxidase Levels around Implants versus Natural Teeth with the Impact of Aloe Vera", International Journal of Science and Research (IJSR), Volume 6 Issue 6, June 2017, pp. 1701-1705, https://www.ijsr.net/getabstract.php?paperid=ART20174600, DOI: https://www.doi.org/10.21275/ART20174600