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Research Paper | Pharmaceutical Science | India | Volume 6 Issue 5, May 2017
Evaluation of Rational use of Antibiotics for Surgical Prophylaxis
Shubham Babu Gupta [4] | S. Sangeetha [4] | G. Sudha Rani | M.Gopi | Mehraj Fatima [3]
Abstract: Background Rational antibiotic prophylaxis reduces the incidence of surgical site infection. Widespread over usage and inappropriate use of antibiotic contribute to increase in the antibiotic resistant organisms. Aim To evaluate the rational use of antibiotics as surgical prophylaxis and assess the patient knowledge regarding the usage of antibiotics. Methods This was a prospective, observational study in which a total of 250 in patients subjected for surgical procedures in gynecology and obstetrics, orthopedics and general surgery admitted in Malla reddy Narayana hospital, Hyderabad were included. The study has begun with the approval of ethics committee. Results We assessed 250 cases of which 75 gynecology and obstetrics surgical cases of which 33.3 % & 36 % of Pre & Post-operative antibiotics were according to guidelines and 66.6 % & 64 % were deviated, Out of 75 orthopedic cases 28 % & 44 % of Pre & Post OP are as per guidelines were as 72 % & 56 & were not.100 General surgery cases were assessed & found to be Pre & Post- OP cases 58 % & 82 % were as per guidelines where as 34 % of Pre & 17 % of Post OP deviated from guidelines. Conclusion The current study revealed that there is inappropriate usage of antibiotics both preoperatively and post operatively. The most common mistake was selection of antibiotic which deviated from guidelines. Patient counseling regarding the antibiotic usage is also important.
Keywords: Prophylaxis, Surgical site infection, Rational use, Resistant strains, ASHP guidelines
Edition: Volume 6 Issue 5, May 2017,
Pages: 1946 - 1950