Prevalence of Antifungal Resistant Strains of Candida Species in Immunocompromised Patients

Dr. Jyoti Dasharath Magare, Dr. R. S. Awasthi

Abstract: The invitro susceptibilities of 50 Candida species isolates were tested against two antifungal agents by a disc diffusion of CLSI M44-A2 method for fungal susceptibility testing. The Candida species shows resistance towards Amphotericin B and fluconazole. According to the results obtained, candida albicans was the, most frequently isolated with 86 %, this was followed by C. tropicalis 4 %, C. krusie 2 % and C. parapsilosis 2 %. In the current study it is found that a number of Candida isolates resistant to amphotericine B were 46.5 % where as 11.9 % strains were interpreted as semi dose dependent and non-albicans Candida all showed 100 % resistance to Amphotericine B. However, the study with fluconazole shows 65 % of Candida isolates were resistant whereas, non-albicans candida all showed 100 % resistance.

Keywords: Candida species, fungal susceptibility, immunocompromised

How to Cite?: Dr. Jyoti Dasharath Magare, Dr. R. S. Awasthi, "Prevalence of Antifungal Resistant Strains of Candida Species in Immunocompromised Patients", Volume 6 Issue 4, April 2017, International Journal of Science and Research (IJSR), Pages: 1786-1788, https://www.ijsr.net/getabstract.php?paperid=ART20172677, DOI: https://dx.doi.org/10.21275/ART20172677