Downloads: 112 | Views: 143 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper | Medicine Science | India | Volume 6 Issue 3, March 2017
Effect of Intraoperative Dexmedetomidine Infusion on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy under General Anaesthesia
Divanshu Gupta | Mamta Sharma [5] | Poonam Kalra [3] | Shobha Purohit [2] | Siddharth Sharma [8]
Abstract: Background-Post-operative nausea and vomiting (PONV) is the most frequently encountered complication after laparoscopic cholecystectomy. The evidence regarding the effect of dexmedetomidine in decreasing PONV is insufficient. The aim of this study was to evaluate the effect of dexmedetomidine infusion as an adjuvant to general anaesthesia on PONV after laparoscopic cholecystectomy. Methods- One hundred twenty ASA grade 1 & 2 adult patients scheduled for elective laparoscopic cholecystectomy were randomly allocated to receive either dexmedetomidine infusion 0.5 mcg/kg/hr (groupA-n=60) or normal saline infusion (groupB-n=60). The incidence and severity of PONV were assessed during first 24 hours postoperatively. The need for postoperative rescue antiemetic was also recorded. Results- The demographic profile of patients were comparable in both groups. VRS score of nausea (1.20.9) was significantly less in group A, as compared to group B (6.71.7), (3.11.2). Moreover the number of episodes of vomiting and retching were significantly reduced in group A as compared to group B, p value (0.0096), (0.0033) respectively. Twenty one percent of patients in group A and fifty eight percent patients in group B required rescue antiemetic in postoperative period. Conclusion-Dexmedetomidine infusion when used as an adjuvant to general anaesthesia reduces the incidence and severity of PONV during first 24 hours after laparoscopic cholecystectomy
Keywords: DEXMEDETOMIDINE, POSTOPERATIVE NAUSEA AND VOMITING, LAPAROSCOPIC CHOLECYSTECTOMY
Edition: Volume 6 Issue 3, March 2017,
Pages: 1826 - 1830
Similar Articles with Keyword 'DEXMEDETOMIDINE'
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Comparative Studies, Medicine Science, India, Volume 12 Issue 4, April 2023
Pages: 1146 - 1149Comparison of Dexmedetomidine and Clonidine as an Adjuvant to Bupivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgeries
Devulapalli Janardhana Pradeep | Subhaprada Satapathy | Rasulata Swain | Ayesha Pattnaik
Downloads: 46
Research Paper, Medicine Science, India, Volume 6 Issue 5, May 2017
Pages: 690 - 693Comparison of Intraoperative and Post-Operative Outcome between Intrathecal Ropivacaine and Ropivacaine with Dexmedetomidine for Lower Limb Surgeries
Larissa D'Silva | Balakrishna Achar