International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 93 | Views: 139

Research Paper | Biology | India | Volume 3 Issue 5, May 2014

Protein Based on its Sequence or Structure to an Existing Protein Family

Manish Kumar [35] | Ajay Prakash [3]

Abstract: To discover a new protein we have suggested some methods and also we have proposed how we can review of a protein to an existing protein family. We generally accepted that the three-dimensional structure of a peptide chain is determined by its amino acid sequence. Still; similar folds can have very different sequences. The ultimate task in sequence analysis is to predict the structure and function of a protein based on its sequence. When the protein of interest shares at least 30 % amino acid identity with another protein; then these two proteins generally exhibit similar three-dimensional structure [1]. But when the proteins have the similar structure but divergent sequences; then the consensus sequence motifs can be used to assess the function of an unassigned sequences. Then these consensus motifs usually correspond to the residues interacting with the cofactors; substrate; or other proteins. In this paper we have also done statistical analysis (through SPSS) to classify identical proteins and Evolutionary Relationship and Structural similarity of the proteins.

Keywords: Protein, PIR, SCOP, CATH, Pfam, Superfamilies

Edition: Volume 3 Issue 5, May 2014,

Pages: 1582 - 1585

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