Survival Analysis of HIV Infected People on Antiretroviral Therapy at Mizan-Aman General Hospital; Southwest Ethiopia

Tezera Moshago, Demissew Berihun Haile, Fikire Enkusilasie

Abstract: Provision of intervention with antiretroviral therapy has significantly changed the course of the AIDS epidemic form to less life-threatening chronic disease. Thus; the study was aimed at assessing the survival and risk factors of death in people living with HIV/AIDS after initiation of antiretroviral therapy at the Hospital. A retrospective cohort study design was applied in this study. The cohort was stratified into three age groups: children; adolescents; and adults. Kaplan-Meier method was effectively run to estimate survival after initiation of ART. Hazard ratio and Cox proportional-hazard regression model were used to determine predictors of survival time to death. The cumulative probability of survival time at the 6th months after initiation of ART was 96 % and 94 %; 96 % and 96 % for children; adolescents and adults respectively (95 %CI). Mortality was significantly higher among patients with a low initial CD4; advanced WHO clinical disease stage III and IV; INH Prophylaxis; TB infection and bedridden. The present study has shown that there has been low cumulative incidence of mortality for HIV patients. Higher priority should be given to HIV-infected individuals by starting ART therapy during the preliminary stage of their illness.

Keywords: ART, Survival analysis, Cohort, Retrospective, Ethiopia

How to Cite?: Tezera Moshago, Demissew Berihun Haile, Fikire Enkusilasie, "Survival Analysis of HIV Infected People on Antiretroviral Therapy at Mizan-Aman General Hospital; Southwest Ethiopia", Volume 3 Issue 5, May 2014, International Journal of Science and Research (IJSR), Pages: 1462-1468, https://www.ijsr.net/getabstract.php?paperid=20132103, DOI: https://dx.doi.org/10.21275/20132103