Estimation of Dose Received by Sensitive Organs in External Radiation Therapy of Cervical Carcinoma
Abstract: The main objective of this study was to estimate dose received by sensitive organs in cervical carcinoma irradiation; out of 200 patients referred to Radiation and Isotopes Center of Khartoum (RICK). After successful investigations; the patients were decided to receive a radical radiotherapy course for stage I and II without hematologic spread. The collected variables were the organs position and depth; patients separations; equivalent field size; percentage depth dose DD % and back scatter factor. The graphs and correlation were carried out using EXCELL software and the analysis of results showed that: the bladder; cervix and rectum were situated parallel to each other from anterior to posterior respectively and they have linear correlation in depth wise with patient separation based in equation: y = 0.38x + 5.56; y = 0.39x + 1.82; y = 0.4x 1.74 respectively; where y refers to organ depth and x refers to patient separation in cm with a significant correlation at R2 = 0.8. The DD % for the tumor (cervix) ; Bladder; head of femur and the rectum were 89.6 %; 61.2; 50.2 % and 38.1 % respectively. The back scattered radiation increases as the tissue volume increases leading to increment of DD % and the back scatter factor increases exponentially with field size increment based on the following equation: y = 0.022lnx + 0.98; which is so significant at R2 = 0.7; where y refers to BSF and x refers to equivalent field size in cm.
Keywords: External radiation, cervix, cancer, toxicity, estimation
How to Cite?: Mohamed E. M. Gar-Alnabi, Enaam A. Mohamed, Mohamed A. Ali Omer, Ghada A. E. Sakin, Mohammed Farahna, "Estimation of Dose Received by Sensitive Organs in External Radiation Therapy of Cervical Carcinoma", Volume 3 Issue 6, June 2014, International Journal of Science and Research (IJSR), Pages: 1694-1698, https://www.ijsr.net/getabstract.php?paperid=13061402, DOI: https://dx.doi.org/10.21275/13061402